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Bromazepam is an anti-anxiety agent with similar side effects to diazepam. It is used to treat anxiety or panic states, bromazepam may be used as a premedicant prior to minor surgery.
How to take Lexotan:
Lexotan is usually not indicated in children, but if the physician feels Lexotan treatment is appropriate, then the dose should be adjusted to their low body-weight (about 0.1–0.3 mg/kg body-weight)
Average dosing for outpatient therapy: 1.5–3 mg up to three times daily.
Severe cases, especially in hospital: 6–12 mg two or three times daily.
Lexotan must not be administered to patients with known hypersensitivity to benzodiazepines, severe respiratory insufficiency, severe hepatic insufficiency.
Benzodiazepines are not indicated to treat patients with severe hepatic insufficiency as they may cause encephalopathy) or sleep apnea syndrome.
Amnesia: Benzodiazepines may induce anterograde amnesia. Anterograde amnesia may occur using higher therapeutic dosages (documented at 6 mg),the risk increasing at higher dosages.
It may be useful to inform the patient when treatment is started that it will be of limited duration and to explain precisely how the dosage will be progressively decreased.
It is important that the patient should be aware of the possibility of rebound phenomena that may occur while the drug is being discontinued
General precautions: The patient should be checked regularly at the start of treatment in order to minimize the dosage and/or the frequency of administration and to prevent overdose due to accumulation.
When benzodiazepines are used,withdrawal symptoms may develop when changing to a benzodiazepine with a considerably shorter elimination half-life
Benzodiazepines should not be used alone to treat depression or anxiety associated with depression (suicide may be precipitated in such patients).
Benzodiazepines are not recommended for the primary treatment of psychotic illness
Cardiac failure including cardiac arrest
Nausea, vomiting, constipation
Hypersensitivity, anaphylactic shock, angioedema
Confusional state, emotional disorder, libido disorders, drug dependence, drug abuse, withdrawal syndrome
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