Saizen for sale online
Saizen [somatropin (rDNA origin) injection] is a human growth hormone produced by recombinant DNA technology.
Saizen has 191 amino acid residues and a molecular weight of 22,125 daltons. Its amino acid sequence and structure are identical to the dominant form of human pituitary growth hormone.
Saizen is available in 5 mg and 8.8 mg vials. The quantitative composition per vial is as follows:
5 mg (approximately 15 IU) vial: Each vial contains 5.0 mg somatropin (approximately 15 IU), 34.2 mg sucrose and 1.16 mg O-phosphoric acid.
8.8 mg (approximately 26.4 IU) vial: Each vial contains 8.8 mg somatropin (approximately 26.4 IU), 60.2 mg sucrose and 2.05 mg O-phosphoric acid. The pH is adjusted with sodium hydroxide or Ophosphoric acid
Pediatric Patients: Saizen [somatropin (rDNA origin) injection] is indicated for the long-term treatment of children with growth failure due to inadequate secretion of endogenous growth hormone
1. Adult Onset: Patients who have growth hormone deficiency either alone, or associated with multiple hormone deficiencies (hypopituitarism), as a result of pituitary disease, hypothalamic disease, surgery, radiation therapy, or trauma; or
2. Childhood Onset: Patients who were growth hormone deficient during childhood who have growth hormone deficiency confirmed as an adult before replacement therapy with Saizen is started.
Somatropin should not be used for growth promotion in pediatric patients with closed epiphyses.
Somatropin is contraindicated in patients with active proliferative or severe non-proliferative diabetic retinopathy.
In general, somatropin is contraindicated in the presence of active malignancy. Any pre-existing malignancy should be inactive and its treatment complete prior to instituting therapy with somatropin
Since growth hormone deficiency may be an early sign of the presence of a pituitary tumor (or, rarely, other brain tumors), the presence of such tumors should be ruled out prior to initiation of treatment.
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